Juvenile-HD
Clinical Definition & Search

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INDEX Page
Tools For Viewing
10 The Most Commonly Asked Questions
Clinical Trials & Research
Huntington's Disease~WeMove Info
Advocacy/Donations/Press Info
Clinical Definition & Search
Facing HD~Family Handbook
JHD Handbook-Chapter 1
JHD Info-Stanford Univ.
Physician's Guide To HD
Caring for People with HD
Physical & Occupational Therapy In HD
Understanding Behaviour in HD-Dr. Jane Paulsen
Understanding Behavioral-Dr. Edmond Chiu
Advanced Stages Caregivers Handbook
First Shift-Certified Nursing Assistants
Activities of Daily Living-HD
Unified HD Rating Scale (UHDRS) Motor Section
Westphal Variant
SECTION 1 - AT RISK
Age & Probability Chart
At Risk For HD-What Next?
At-Risk Checklist
Best Interest of Child?
Crystal Ball?
Food For Thought
Parent Hasn't Tested?
Q&A On Risk of Inheriting JHD
Testing Children
SECTION 2 - GENETIC TESTING
Genetic Disorders & Birth Defects
Genetic Testing for HD
Genetic Counseling-In General
Psychological Impact
Intro: Genetics/Genetic Testing
Prenatal & Preimplanation
Prenatal Testing-In General
o Genetic Testing Resources
o Personal Stories
SECTION 3 - JHD
Coping With The Early Years
Age of HD Appearance
Age of Onset-Historical
Family-HD Underestimated
Children of Parents With HD
Child~Parent Ill
Clinical Description JHD
HD - What Kids Are Saying
HD & Me
JHD-Duration of Illness
JHD-Clinical and Research
JHD Symptoms
Parenting With HD
Patients/Families Coping
Talking With Children About HD
5 Stages of HD
JHD Resources
SECTION 4 - SYMPTOM RECOGNITION
Parent Resources
8 Fears of A Chronic Illness
Anxiety/Apathy/Irritability~HD
Anxiety, Fears & Phobias
Apathy-Physician's Guide
Ataxia
Attention-Perceptual/Unawareness Physician's Guide
Bed/Pressure Sores
Bed/Pressure Ulcer Guideline
Behavior Management
Bi-Polar Disorders
Botulinum toxin therapy
Bradykinesia
Caring Tips
Child Abuse-Reconizing Signs
Chorea-Physician's Guide
Chorea
Cognitive/Decision Making/Impulsivity
Cognitive-Short Tips
Contractures~Joints Locking
Dehydration-Physician's Guide
Dehydration
Delirium
Denial of HD
Depression~Physician's Guide
Depression-Understanding It
Depression-How To Help
Depression - Treatment Resistant Patient
Depression-Other Resources
-Read If Your Child Is On Antidepressant
Disgust - Impaired Recognition in HD
Dissociative disorders
Driving - Physician's Guide
Dyslexia
Dyslexia Resources
Dystonia
Dystonia/Rigidity & Spasticity Physician's Guide
Dystonia-Predominant Adult-Onset HD
Epileptic Seizures and Epilepsy
Epilepsy-Seizures~PG
-Seizures ~Special Populations
Falling~Safety
Falling - Subdural Hematoma Risk
Fevers - Unexplained
Fevers, sweating & menstural cycles in HD
GERD (Stomach)
HD Principle Treatments
Hallucinations/Psychosis~PGHD
Hand muscle reflexes in HD
Hypothalamus - A Personal Theory
Insomia ~Physician's Guide
Irritability~Temper Outburst Physician's Guide
Learning Disability
Mania/OCD~Physician's Guide
Mood Disorder Rate In HD
Myoclonus (Movements)
Nails-What To Look For
Night Terrors
Obsessive Compulsive OCD
Panic Disorder
Personality disorders
Pneumonia
Pneumonia-Advanced Stages
Pneumonia - Aspirated (Inhaled)
Prosody - Social Impairment
Sexuality~Physician's Guide
Skins Sensitivity
Sleep Disorders
Smoking-Physician's Guide
Spasticity
Stress
Tremors
Why Certain Symptoms Occur
Symptom & Treatment Resources
SECTION 5 - COMMUNICATION
Communication Resources
Communication Problems
Communication Strategies For HD~Jeff Searle
SECTION 6 - EATING/SWALLOWING/NUITRITION
Hints For Weight Loss in HD
HD & Diet~HSA Fact Sheet 7
Nutrients: Some Possible Deficiency Symptoms
Nutrition and HD~Anna Gaba (Recipes)
Nutrition Information In HD~Naomi Lundeen
Speech & Swallowing~Lynn Rhodes
Swallowing & Nutrition Physician's Guide To HD
Swallowing & Nuitrition Resources
Swallowing Warning Signs
5 Swallowing Problems
Taste changes in HD
Weight Gain
Resources-Drinks/Shakes
-Feeding Tubes~Advanced Stages of HD
-Feeding Tube~Jean Miller
-Feeding Tubes: One More Word ~Jean Miller
-Feeding Tubes & Baby Foods
-Feeding Tube~Dental Care
-Feeding Tube Instructions~Jean Miller
-Feeding Tube Resources
SECTION 7 - THERAPIES
Finding a Therapist - Behavoir
What Is A Physiotherapist?
Physical Therapy In HD
Speech-Language Therapy
Therapy Descriptions
Therapy Resources- Easter Seal
Therapy Resources
SECTION 8 - MEDICATIONS
HD Treatments
Medications-Movement Disorders
Medication/Emergency Info Forms
Cutting Prescriptions
Drugs-Look 'Em Up
-Adolescents Under 25
-Antidepressant Adverse Effects
-Anti-psychotic
-Anxiety-Antidepressant
A-Z Mental Health Drugs
-Creatine
-EPA~Fish Oil
-Haldol/Haloperidol - Clinical Sheet
-Haldol~Clinician Description
-Haldol & HD
-Haldol/HD Patient Experiences
-Haldol~ Patient Handout
-Mood Stabilizers: ASK 3 Questions
-Neuroleptic Malignant Synd WARNING
-Olanzipine-Risperidone/blood tests
-Celexa/Luvox/Paxil/Prozac/Zoloft
-Psychiatric Drugs & Children
Sertraline ~Zoloft
-Spasticity Meds/Treatments
-SSRI Medications
-Tardive Dyskinesia WARNING
-Weight Gain Medications
-Sites/Help the Medicine Go Down
-Vitamin & Mineral Deficiencies
SECTION 9 - SURGERIES
Surgery-Movement Disorders
o Surgery Resources
SECTION 10 - PROCEDURES
Clinic Visits-How To Prepare
CT Scans, MRI's etc.
Swallowing Tests
Tests Commonly Used
o Procedures Resources
SECTION 11- ALCOHOL/DRUGS
Alcohol-Parent's Guide
Alcohol-Talking To Your Child
Drugs-What To Do?
Drugs-Talking To Your Child
Disciplining-Ages 0-13 & Up
SECTION 12- SUICIDE
Straight Talk On Suicide
Teen Suicide-You Need To Know
o Suicide Resources
SECTION 13 - DIVORCE
Divorce & Child Stress
Tips For Divorcing Parents
SECTION 14 - DISABILITY ISSUES
Guides To Disability Issues
Caring-Child & Medical Technology
Caring for a Seriously Ill Child
Child Long Term Illness
Disability-Special Education Plan
IFSP Early Intervention Process
Disability Resources
Financial Planning
Wishes Can Come True-Children's Wish Foundations
Special Needs Resources
Special Needs Camp - About
Special Needs Camp - Finding One
SECTION 15 - ASSISTIVE TECHNOLOGY
Child Assistive Technology
Adaptive Equipment Resources
Products
SECTION 16 - EMOTIONAL ISSUES
Signs of Unhealthy Self-Esteem
Emotional Behavior Links
o Emotional Support Resources
SECTION 17 - GRIEF
Helping Child Deal With Death
o Grief Addtional Resources
SECTION 18 - ADD/ADHD
ADD & Teens
Conduct Disorders
FAQS & Related Info
Understanding AD/HD
What Is AD/HD?
Research Articles
Resources
SECTION 19 - HD SUPPORT GROUPS
HD Support Groups
National Youth Association
SECTION 20 - HD LINKS
HD Links
Related Resources
Tips For Friends
SECTION 21 - BENEFITS/INSURNACE
HD Disability
Benefits Check UP - See What You Can Get
Medical Insurance Bureau's Facts On You!
Medicare-Medicaid
Medicare Rights-Home Health & Hospice
Medicare Rights Center Resources
No Insurance? Try This!
Prescription Drug Cards Part I
Prescription Drug Cards Part II
Social Security-Children With Disabilities
SECTION 22 - ARTICLES/JHD
JHD and ADD
SECTION 23 - CAREGIVING
Articles-Resources
Caregiver Self-Assessment
Caregiver's Handbook
"First Shift With A Person With HD"
Getting Respite Care/Help At Home
Helpful Forms-Info
Home Emergency Preparations
Symptom Management
Ten Tips
Useful Tools
SECTION 24 - BIO
Our Personal Experience
Coping At The End
Kelly E. Miller
Song & Verse
Letter From My Heart
GUESTBOOK

INDEX Page

Clinical Definitions & Search
 
Actually this list is too long to include in this website so the information has been placed on another site and linked here.
 
I started the accumulating these definition which are sometimes used to describe symptoms of/or tests for HD or discuss other diseases or condition which have symptoms similar to Huntington's Disease. 
 
So pour a cup of coffee and sit a spell while you read through these. Many explain the explicit terminology for a symptom of HD your loved one may be experiencing, like ataxia, chore, dysarthria etc. which would be helpful for you to know when speaking with physician's and therapist in describing a particular problem.
 
Symptoms
Scientific/Technical
Testing
Drug
Other diseases similiar to HD
 
 

Other Problems or Diseases to be Considered
 
Huntington disease, Huntington's disease, HD, Huntington's chorea, HC Authored by J Stephen Huff, MD, Associate Professor of Emergency Medicine and Neurology, Department of Emergency Medicine, University of Virginia Health System Source: http://www.emedicine.com/emerg/topic254.htm
  • Hereditary nonprogressive chorea
  • Neuroacanthocytosis
  • Wilson disease
  • Ataxia-telangiectasia
  • Lesch-Nyhan syndrome
  • Hallervorden-Spatz disease
  • Fahr disease
  • Sydenham chorea
  • Drug-induced movement disorder
  • Chorea gravidarum
  • Hyperglycemic nonketotic encephalopathy
  • Hemichorea/hemiballism with subthalamic nucleus lesion
  • Periarteritis nodosa
  • Senile chorea
  • Essential chorea
  • Parkinson disease
  • Alzheimer disease
  • Creutzfeldt-Jakob disease
  • Pick disease
  • Bipolar disorder
  • Alcoholism
  • Antisocial personality disorder
  • Huntington Chorea
 
________________________________________
 
8 CAG Repeat Expansion Disorders
 
To date, eight such inherited neurological disorders have been identified to be caused by CAG repeat expansion in their respective genes;
  • Huntington's Disease
  • Dentatorubral pallidoluysian atrophy (DRPLA)
  • Spinobulbar muscular atrophy (SBMA)
  • Spinocerebellar ataxia types 1, 2, 3, 6 and 7
  • (SCA1, SCA2, SCA3, SCA6 and SCA7).
These diseases share certain features, which include neurodegeneration, a dominant pattern of inheritance and genetic anticipation. The CAG trinucleotide repeats in all these genes are found in the coding region and is translated into a string of polyglutamines.
 
Despite the widespread tissue distribution of the transcript and protein for
each of these genes, the affected region is primarily the brain and the
regions of neuronal loss are highly selective and specific for any of these
diseases.
 
_________________________________________
 
DIFFERENTIAL DIAGNOSIS
Differential diagnosis includes hepatocerebral degeneration, schizophrenia with tardive dyskinesia, other chorea's,  and drug reactions.
_________________________
 
SEARCH ENGINE
 
Or you can use this search engine:
 
From the DNA Learning Center at Cold Spring Harbor Laboratory Definitions provided by the National Institutes of Health
 
GLOSSARY
(Definitions of words describing genetic disorders and birth defects.)

Click on a letter to jump to a disorder beginning with that letter
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X Y Z
 

A Quick TUTORIAL

How to Translate Medical Terms into Understandable English 
There are simple words, called root words, that describe simple objects or processes. To describe something more complex, another root word is often added in front of it (a prefix) or following it (a suffix). To decypher or translate a term into plain English, it must first be broken down into individual Latin words. This can be done with the section on "Prefixes, Suffixes, and Root Words" found on above site.
 
Huntington's Disease Glossary
Source: YourGenesYourHealth
 
Adenine: One of the four bases that make up DNA. Abbreviated with an 'A'.

Base: A small molecule inside the larger molecule of DNA. Bases - A, C, G, and T - are arranged in line in a DNA molecule (e.g. CGGTACAGG) and encode instructions for making proteins.

CAG: Triplet codon that codes for glutamine. The number of CAG repeats is
higher in the IT-15 gene of people with Huntington.

Chromosome: Chromosomes are packages of DNA found in the nucleus of cells. Humans have 46 chromosomes.

Codon: Three letters of bases in a gene that encode the type of amino acid to be placed in the protein. For example, the codon G-T-G signifies the amino
acid valine.

Cytosine: One of the four bases that make up DNA. Abbreviated with a 'C'.

DNA: Short for deoxyribonucleic acid, DNA is the molecule that carries genetic information.

Dominant: A genetic trait or disorder is dominant when only one copy of the
mutated gene is necessary for the trait to develop. A recessive trait or disorder develops when two copies of the mutated gene are inherited.

Enzyme: Protein that helps other chemical reactions in the body proceed.

Exon: A section of a gene that contains the instructions for making a protein.

Gel: Hard Jello-like substance that scientists use to measure the size of DNA
fragments during DNA diagnostic tests.

Gene: A portion of DNA that contains instructions for making a protein.

Genotype: The genetic composition of a person. Usually used when considering one gene or chromosome (e.g., males have a XY genotype, females have a XX).

Glutamine: One of 20 amino acids. People with Huntington have more glutamines in the huntingtin protein because of the increased number of CAG repeats.

Guanine: One of the four bases that make up DNA. Abbreviated with a 'G'.

Huntingtin: The protein made by the IT-15 gene. People with Huntington have a huntingtin protein with more glutamines.

Intron: A section of a gene that does not contain any instructions for making a protein. Introns separate exons -- the coding sections -- from each other.

Mutation: A change in the genetic code (the A's, C's, G's and T's) of a gene.

PCR/Polymerase chain reaction: A method to increase or amplify specific sections of DNA. This method can be used to detect changes in genes that cause genetic disorders.

Primer: A small DNA molecule used to perform PCR.

Protein: A type of molecule produced by the body. The instructions for producing proteins reside in the genes.

Punnett square: A method of showing the potential offspring of two parents.

Recessive: Refers to genetic disorders in which a person must have two copies of the mutated gene to develop the disorder.

Thymine: One of the four bases that make up DNA. Abbreviated with a 'T'.