Clinical Definitions & Search
Actually this list is too long to include in this website so the information has been placed on another site and linked here.
I started the accumulating these definition which are sometimes used to describe symptoms of/or tests for HD or discuss other diseases or condition which have symptoms similar to Huntington's Disease.
So pour a cup of coffee and sit a spell while you read through these. Many explain the explicit terminology for a symptom of HD your loved one may be experiencing, like ataxia, chore, dysarthria etc. which would be helpful for you to know when speaking with physician's and therapist in describing a particular problem.
Symptoms
Scientific/Technical
Testing
Drug
Other diseases similiar to HD
Other Problems or Diseases to be Considered
Huntington disease, Huntington's disease, HD, Huntington's chorea, HC Authored by J Stephen Huff, MD, Associate Professor of Emergency Medicine and Neurology, Department of Emergency Medicine, University of Virginia Health System Source: http://www.emedicine.com/emerg/topic254.htm
- Hereditary nonprogressive chorea
- Neuroacanthocytosis
- Wilson disease
- Ataxia-telangiectasia
- Lesch-Nyhan syndrome
- Hallervorden-Spatz disease
- Fahr disease
- Sydenham chorea
- Drug-induced movement disorder
- Chorea gravidarum
- Hyperglycemic nonketotic encephalopathy
- Hemichorea/hemiballism with subthalamic nucleus lesion
- Periarteritis nodosa
- Senile chorea
- Essential chorea
- Parkinson disease
- Alzheimer disease
- Creutzfeldt-Jakob disease
- Pick disease
- Bipolar disorder
- Alcoholism
- Antisocial personality disorder
- Huntington Chorea
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8 CAG Repeat Expansion Disorders
To date, eight such inherited neurological disorders have been identified to be caused by CAG repeat expansion in their respective genes;
- Huntington's Disease
- Dentatorubral pallidoluysian atrophy (DRPLA)
- Spinobulbar muscular atrophy (SBMA)
- Spinocerebellar ataxia types 1, 2, 3, 6 and 7
- (SCA1, SCA2, SCA3, SCA6 and SCA7).
These diseases share certain features, which include neurodegeneration, a dominant pattern of inheritance and genetic anticipation. The CAG trinucleotide repeats in all these genes are found in the coding region and is translated into a string of polyglutamines.
Despite the widespread tissue distribution of the transcript and protein for
each of these genes, the affected region is primarily the brain and the
regions of neuronal loss are highly selective and specific for any of these
diseases.
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DIFFERENTIAL DIAGNOSIS
Differential diagnosis includes hepatocerebral degeneration, schizophrenia with tardive dyskinesia, other chorea's, and drug reactions.
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SEARCH ENGINE
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From the DNA Learning Center at Cold Spring Harbor Laboratory Definitions provided by the National Institutes of Health
GLOSSARY
(Definitions of words describing genetic disorders and birth defects.)
Click on a letter to jump to a disorder beginning with that letter
A Quick TUTORIAL
How to Translate Medical Terms into Understandable English
There are simple words, called root words, that describe simple objects or processes. To describe something more complex, another root word is often added in front of it (a prefix) or following it (a suffix). To decypher or translate a term into plain English, it must first be broken down into individual Latin words. This can be done with the section on "Prefixes, Suffixes, and Root Words" found on above site. |
